Difference between revisions of "Anatomical Therapeutic Chemical classification"

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The '''Anatomical Therapeutic Chemical (ATC) classification''' system is used for the [[taxonomic classification|classification]] of [[Medication|drug]]s. It is controlled by the [[World Health Organization|WHO]] Collaborating Centre for Drug Statistics Methodology, and was first published in 1976.<ref name="ATC about">WHO Collaborating Centre for Drug Statistics Methodology: [http://www.whocc.no/atcddd/atcsystem.html About the ATC/DDD system]</ref>
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{{ATC top}}
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The '''Anatomical Therapeutic Chemical (ATC) classification''' system is used for the classification of [[pharmaceutical]]s. The classification system divides drugs into different groups according to the organ or system on which they act and/or their [[medicine|therapeutic]] and [[chemical classification|chemical characteristics]].
  
The classification system divides drugs into different groups according to the organ or system on which they act and/or their [[medicine|therapeutic]] and [[chemical classification|chemical characteristics]].
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It was developed by Norwegian researchers working for the Nordic Council on Medicines (NLN), and first used for statistical purposes in 1976. The [[World Health Organization|WHO]] Regional Office for Europe recommended its use throughout the continent from 1981, and the WHO Collaborating Centre for Drug Statistics Methodology was established in Oslo, funded by the Norwegian government, to coordinate the system. Since 1996, the WHO has recognised the ATC classification as an international standard for compiling statistics on drug use.<ref name="ATC about">{{ATC about | accessdate = 2009-12-05}}.</ref>
  
 
== Classification ==
 
== Classification ==
In this system, drugs are classified into groups at 5 different levels:<ref name="ATC about" />
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In this system, drugs are classified into groups at 5 different levels:<ref name="ATC about"/>
  
=== First level ===
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;First level: The first level of the code indicates the anatomical main group and consists of one letter: there are 14 main groups.<ref>{{ATC index | accessdate = 2009-12-05}}.</ref>
The first level of the code indicates the anatomical main group and consists of one letter. There are 14 main groups:<ref>WHO Collaborating Centre for Drug Statistics Methodology: [http://www.whocc.no/atcddd/indexdatabase/ ATC/DDD Index]</ref>
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:''Example'': [[ATC code C|'''C''']] Cardiovascular system
  
{| class="wikitable"
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;Second level: The second level of the code indicates the therapeutic main group and consists of two digits.
|-
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:''Example'': [[ATC code C03|C'''03''']] [[Diuretic]]s
!Code
 
!Contents
 
|- style="background:#fd6"
 
| [[ATC code A|'''A''']]
 
| [[Alimentary tract]] and [[metabolism]]
 
|- style="background:MistyRose"
 
| [[ATC code B|'''B''']]
 
| [[Blood]] and [[haematopoiesis|blood forming organs]]
 
|- style="background:MistyRose"
 
| [[ATC code C|'''C''']]
 
| [[Cardiovascular system]]
 
|- style="background:Linen"
 
| [[ATC code D|'''D''']]
 
| [[Dermatological]]s
 
|- style="background:#beb"
 
| [[ATC code G|'''G''']]
 
| [[Genito-urinary system]] and [[sex hormone]]s
 
|- style="background:#efefef"
 
| [[ATC code H|'''H''']]
 
| Systemic [[hormonal]] preparations, excluding sex hormones and insulins
 
|- style="background:PowderBlue"
 
| [[ATC code J|'''J''']]
 
| [[Antiinfective]]s for systemic use
 
|- style="background:Plum"
 
| [[ATC code L|'''L''']]
 
| [[Antineoplastic]] and [[immunomodulator|immunomodulating]] agents
 
|- style="background:Linen"
 
| [[ATC code M|'''M''']]
 
| [[Musculo-skeletal system]]
 
|- style="background:LightYellow"
 
| [[ATC code N|'''N''']]
 
| [[Nervous system]]
 
|- style="background:PowderBlue"
 
| [[ATC code P|'''P''']]
 
| [[Antiparasitic]] products, [[insecticide]]s and [[insect repellent|repellent]]s
 
|- style="background:MistyRose"
 
| [[ATC code R|'''R''']]
 
| [[Respiratory system]]
 
|- style="background:LightYellow"
 
| [[ATC code S|'''S''']]
 
| [[Sensory organ]]s
 
|- style="background:#ccf"
 
| [[ATC code V|'''V''']]
 
| Various
 
|}
 
  
=== Second level ===
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;Third level: The third level of the code indicates the therapeutic/pharmacological subgroup and consists of one letter.
The second level of the code indicates the therapeutic main group and consists of two digits.
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:''Example'': C03'''C''' High-ceiling diuretics
  
''Example'': [[ATC code C03|C'''03''']] [[Diuretic]]s
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;Fourth level: The fourth level of the code indicates the chemical/therapeutic/pharmacological subgroup and consists of one letter.
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:''Example'': C03C'''A''' [[Sulfonamide]]s
  
=== Third level ===
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;Fifth level: The fifth level of the code indicates the chemical substance and consists of two digits.
The third level of the code indicates the therapeutic/pharmacological subgroup and consists of one letter.
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:''Example'': C03CA'''01''' [[Furosemide]]
  
''Example'': C03'''C''' High-ceiling diuretics
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=== ATCvet ===
 
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The Anatomical Therapeutic Chemical Classification System for veterinary medicinal products (ATCvet) is used to classify [[veterinary]] drugs. It was first developed by the Nordic Council on Medicines (NLN) in 1992, and has been coordinated by the WHO Collaborating Centre for Drug Statistics Methodology since 2001.<ref name="ATCvet about">{{ATCvet about | accessdate = 2009-12-05}}.</ref>
=== Fourth level ===
 
The fourth level of the code indicates the chemical/therapeutic/pharmacological subgroup and consists of one letter.
 
 
 
''Example'': C03C'''A''' [[Sulfonamide]]s
 
  
=== Fifth level ===
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Many medicinal products have both human and veterinary uses. ATCvet codes can be created by placing the letter Q in front of the ATC code of most human medications. For example, furosemide for veterinary use has the code '''Q'''C03CA01.
The fifth level of the code indicates the chemical substance and consists of two digits.
 
  
''Example'': C03CA'''01''' [[Furosemide]]
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Some codes are used exclusively for veterinary drugs, for example ''[[ATCvet code QI|QI]] Immunologicals'', ''[[ATCvet code QJ51|QJ51]] Antibacterials for intramammary use'' or ''QN05AX90 [[amperozide]]''.<ref name="ATCvet about"/>
 
 
=== ATCvet ===
 
The ''Anatomical Therapeutic Chemical Classification System for veterinary medicinal products'' (ATCvet) is used to classify [[veterinary]] drugs. ATCvet codes can be created by placing the letter Q in front of the ATC code of most human medications. For example, furosemide for veterinary use has the code '''Q'''C03CA01.
 
 
 
Some codes are used exclusively for veterinary drugs, like ''[[ATCvet code QI|QI]] Immunologicals'', ''[[ATCvet code QJ51|QJ51]] Antibacterials for intramammary use'' or ''QN05AX90 [[amperozide]]''.<ref>WHO Collaborating Centre for Drug Statistics Methodology: [http://www.whocc.no/atcvet/about_atcvet.html About the ATCvet classification system]</ref>
 
  
 
== Defined Daily Dose ==
 
== Defined Daily Dose ==
 
{{main|Defined Daily Dose}}
 
{{main|Defined Daily Dose}}
The ATC system also includes Defined Daily Doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults."<ref name="ATC about" />
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The ATC system also includes Defined Daily Doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults."<ref name="ATC about"/>
  
 
== References ==
 
== References ==
Line 90: Line 37:
  
 
== External links ==
 
== External links ==
* [http://www.whocc.no/atcddd Official ATC website], hosted by the WHO Collaborating Centre for Drug Statistics Methodology
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* [http://www.whocc.no/atcddd Official ATC website]
 
* [http://www.fmrc.org.au/atc/index.htm ATC: Introduction] on the Family Medicine Research Centre, University of Sydney
 
* [http://www.fmrc.org.au/atc/index.htm ATC: Introduction] on the Family Medicine Research Centre, University of Sydney
  
{{Major Drug Groups}}
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[[Category:Pharmaceuticals]]
 
 
[[Category:Drugs]]
 
 
[[Category:ATC codes| ]]
 
[[Category:ATC codes| ]]
[[Category:Drugs_by_target_organ_system| ]]
 
[[Category:Pharmacological classification systems]]
 
  
 
{{Imported from Wikipedia|name=Anatomical Therapeutic Chemical Classification System|id=327035313}}
 
{{Imported from Wikipedia|name=Anatomical Therapeutic Chemical Classification System|id=327035313}}

Latest revision as of 06:54, 5 December 2009

The Anatomical Therapeutic Chemical (ATC) classification system is used for the classification of pharmaceuticals. The classification system divides drugs into different groups according to the organ or system on which they act and/or their therapeutic and chemical characteristics.

It was developed by Norwegian researchers working for the Nordic Council on Medicines (NLN), and first used for statistical purposes in 1976. The WHO Regional Office for Europe recommended its use throughout the continent from 1981, and the WHO Collaborating Centre for Drug Statistics Methodology was established in Oslo, funded by the Norwegian government, to coordinate the system. Since 1996, the WHO has recognised the ATC classification as an international standard for compiling statistics on drug use.[1]

Classification

In this system, drugs are classified into groups at 5 different levels:[1]

First level
The first level of the code indicates the anatomical main group and consists of one letter: there are 14 main groups.[2]
Example: C Cardiovascular system
Second level
The second level of the code indicates the therapeutic main group and consists of two digits.
Example: C03 Diuretics
Third level
The third level of the code indicates the therapeutic/pharmacological subgroup and consists of one letter.
Example: C03C High-ceiling diuretics
Fourth level
The fourth level of the code indicates the chemical/therapeutic/pharmacological subgroup and consists of one letter.
Example: C03CA Sulfonamides
Fifth level
The fifth level of the code indicates the chemical substance and consists of two digits.
Example: C03CA01 Furosemide

ATCvet

The Anatomical Therapeutic Chemical Classification System for veterinary medicinal products (ATCvet) is used to classify veterinary drugs. It was first developed by the Nordic Council on Medicines (NLN) in 1992, and has been coordinated by the WHO Collaborating Centre for Drug Statistics Methodology since 2001.[3]

Many medicinal products have both human and veterinary uses. ATCvet codes can be created by placing the letter Q in front of the ATC code of most human medications. For example, furosemide for veterinary use has the code QC03CA01.

Some codes are used exclusively for veterinary drugs, for example QI Immunologicals, QJ51 Antibacterials for intramammary use or QN05AX90 amperozide.[3]

Defined Daily Dose

The ATC system also includes Defined Daily Doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults."[1]

References

  1. 1.0 1.1 1.2 About the ATC/DDD system; WHO Collaborating Centre for Drug Statistics Methodology, <http://www.whocc.no/atcddd/atcsystem.html>. (accessed 5 December 2009).
  2. ATC/DDD Index; WHO Collaborating Centre for Drug Statistics Methodology, <http://www.whocc.no/atcddd/indexdatabase/>. (accessed 5 December 2009).
  3. 3.0 3.1 About the ATCvet classification system; WHO Collaborating Centre for Drug Statistics Methodology, <http://www.whocc.no/atcvet/about_atcvet.html>. (accessed 5 December 2009).

External links

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