Nickel Directive

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The Nickel Directive was a European Union directive regulating the use of nickel in jewellery and other products that come into contact with the skin. It has since been subsumed in the REACH Regulation, specifically paragraph 27 of Annex 17 to that regulation.

Allergy to nickel is a common cause of contact dermatitis, with roughly 10% of the population in Western Europe and North America being sensitive to nickel.[1][2][3]

  • Directive 76/769/EEC
  • Directive 94/27/EEC
  • Directive 2004/96/EC

References

  1. Schäfer first1 = T.; Böhler, E.; Ruhdorfer, S.; Weigl, L.; Wessner, D.; Filipiak, B.; Wichmann, H. E.; Ring, J. Epidemiology of contact allergy in adults. Allergy 2001, 56 (12), 1192–96. PMID 11736749.
  2. Krob, H. A.; Fleischer, A. B., Jr.; D'Agostino, R., Jr.; Haverstock, C. L.; Feldman, S. Prevalence and relevance of contact dermatitis allergens: a meta-analysis of 15 years of published T.R.U.E. test data. J. Am. Acad. Dermatol. 2004, 51 (3), 349–53. PMID 15337975.
  3. Thyssen, J. P.; Linneberg, A.; Menné, T.; Johansen, J. D. The epidemiology of contact allergy in the general population—prevalence and main findings. Contact Dermatitis 2007, 57 (5), 287–99. PMID 17937743. DOI: 10.1111/j.1600-0536.2007.01220.x.
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