Difference between revisions of "2-Methylbutan-2-ol"
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{{chembox | {{chembox | ||
| − | | | + | | Name = 2-Methylbutan-2-ol |
| − | | | + | | ImageFile = Tert-pentyl-alcohol-2D-skeletal.png |
| ImageSize = 120px | | ImageSize = 120px | ||
| − | | | + | | IUPACName = 2-Methylbutan-2-ol |
| − | | OtherNames = | + | | OtherNames = ''tert''-Amyl alcohol<br/>Dimethylethylcarbinol<br/>''t''-Amyl alcohol<br/>2-Methyl-2-butanol<br/>''tert''-Pentanol |
| Section1 = {{Chembox Identifiers | | Section1 = {{Chembox Identifiers | ||
| + | | InChI = 1/C5H12O/c1-4-5(2,3)6/h6H,4H2,1-3H3 | ||
| + | | StdInChI = 1S/C5H12O/c1-4-5(2,3)6/h6H,4H2,1-3H3 | ||
| + | | InChIKey = MSXVEPNJUHWQHW-UHFFFAOYAG | ||
| + | | StdInChIKey = MSXVEPNJUHWQHW-UHFFFAOYSA-N | ||
| CASNo = 75-85-4 | | CASNo = 75-85-4 | ||
| CASNo_Ref = {{cascite}} | | CASNo_Ref = {{cascite}} | ||
| − | }} | + | | EC-number = 200-908-9 |
| + | | ChemSpiderID = 6165 | ||
| + | }} | ||
| Section2 = {{Chembox Properties | | Section2 = {{Chembox Properties | ||
| Formula = C<sub>5</sub>H<sub>12</sub>O | | Formula = C<sub>5</sub>H<sub>12</sub>O | ||
| − | | MolarMass = 88. | + | | MolarMass = 88.148 g/mol |
| − | | Density = 0.815 g/ | + | | Density = 0.815 g/cm<sup>3</sup>, liquid |
| Solubility = 120 g/L | | Solubility = 120 g/L | ||
| MeltingPtC = -12 | | MeltingPtC = -12 | ||
| BoilingPtC = 102 | | BoilingPtC = 102 | ||
| − | }} | + | }} |
| − | | | + | | Section7 = {{Chembox Hazards |
| − | | ExternalMSDS = [http://www.jtbaker.com/msds/englishhtml/a6408.htm | + | | Reference = <ref>{{CLP Regulation|index=603-007-00-2|page=477}}</ref> |
| − | | | + | | ExternalMSDS = [http://www.jtbaker.com/msds/englishhtml/a6408.htm Commercial MSDS] |
| − | | | + | | EUIndex = 603-007-00-2 |
| − | | | + | | GHSPictograms = {{GHS02|Flam. Liq. 2}}{{GHS07|Acute Tox. 4; STOT SE 3; Skin Irrit. 2}} |
| − | | | + | | GHSSignalWord = DANGER |
| − | | FlashPt = 19 °C | + | | HPhrases = {{H-phrases|225|335|335|315}} |
| − | | | + | | FlashPt = 19 °C (66 ºF) |
| − | | | + | }} |
| − | }} | + | | Section8 = {{Chembox Related |
| + | | RelatedFunctn = [[Pentan-1-ol]]<br/>[[2-Methylbutan-1-ol]]<br/>[[3-Methylbutan-1-ol]]<br/>[[3-Methylbutan-2-ol]] | ||
| + | | Function = [[pentanol]]s | ||
| + | | RelatedCpds = [[Tert-Butanol|''tert''-Butanol]] | ||
| + | }} | ||
}} | }} | ||
| − | '''2- | + | '''2-Methylbutan-2-ol,''' also known as '''''tert''-amyl alcohol''' or '''''tert''-pentanol''', is one of the [[isomer]]s of [[pentanol]]. It is a clear, colorless liquid with a strong odor of peppermint.<ref>{{citation | last = Coblentz | first = Virgil | title = The Newer Remedies: A reference manual for physicians, pharmacists, and students| year = 1899 | url = http://books.google.com/books?id=BRxKAAAAMAAJ&printsec=titlepage&source=gbs_summary_r&cad=0#PPA18,M1}}.</ref> In humans it possesses [[sedative]] and [[hypnotic]] effects similar to [[ethanol]] through ingestion or inhalation, and was previously used in medicine for this purpose.<ref>{{citation | first = Robert A. | last = Lewis | title = Lewis' Dictionary of Toxicology | year = 1998}}.</ref> It is active in doses of 2,000-4,000 mg, making it some 20 times more potent than regular ethanol.<ref>{{citation | first1 = Hans | last1 = Brandenberger | first2 = Robert A. A. | last2 = Maes | title = Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists | year = 1997 | url = http://books.google.com/books?id=ZhYtynyC4kAC&printsec=frontcover&source=gbs_summary_r&cad=0#PPA401,M1}}.</ref> 2-Methylbutan-2-ol is similar in structure to [[ethchlorvynol]] and [[methylpentynol]]. It is a byproduct of the fermentation of [[grain]]. <ref>{{citation | first1 = George Milbry | last1 = Gould | first2 = R. J. E. | last2 = Scott | title = The Practitioner's Medical Dictionary | year = 1910}}.</ref> |
==References== | ==References== | ||
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{{Sedative}} | {{Sedative}} | ||
| − | {{DEFAULTSORT: | + | {{DEFAULTSORT:Methylbutanol-2, 2-}} |
[[Category:Alcohols]] | [[Category:Alcohols]] | ||
{{Imported from Wikipedia|name=2-Methyl-2-butanol|id=293615491}} | {{Imported from Wikipedia|name=2-Methyl-2-butanol|id=293615491}} | ||
Latest revision as of 08:46, 22 August 2009
| 2-Methylbutan-2-ol | |
|---|---|
| |
| IUPAC name | 2-Methylbutan-2-ol |
| Other names | tert-Amyl alcohol Dimethylethylcarbinol t-Amyl alcohol 2-Methyl-2-butanol tert-Pentanol |
| Identifiers | |
| InChI | InChI=1/C5H12O/c1-4-5(2,3)6/h6H,4H2,1-3H3 |
| InChIKey | MSXVEPNJUHWQHW-UHFFFAOYAG |
| Standard InChI | InChI=1S/C5H12O/c1-4-5(2,3)6/h6H,4H2,1-3H3 |
| Standard InChIKey | MSXVEPNJUHWQHW-UHFFFAOYSA-N |
| CAS number | [] |
| EC number | |
| ChemSpider | |
| Properties | |
| Chemical formula | C5H12O |
| Molar mass | 88.148 g/mol |
| Density | 0.815 g/cm3, liquid |
| Melting point |
-12 °C, 261 K, 10 °F |
| Boiling point |
102 °C, 375 K, 216 °F |
| Solubility in water | 120 g/L |
| Hazards[1] | |
| Material safety data sheet (MSDS) | Commercial MSDS |
| EU index number | 603-007-00-2 |
| GHS pictograms |  
|
| GHS signal word | DANGER |
| GHS hazard statements | H225, H335, H335, H315 |
| Flash point | 19 °C (66 ºF) |
| Related compounds | |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
2-Methylbutan-2-ol, also known as tert-amyl alcohol or tert-pentanol, is one of the isomers of pentanol. It is a clear, colorless liquid with a strong odor of peppermint.[2] In humans it possesses sedative and hypnotic effects similar to ethanol through ingestion or inhalation, and was previously used in medicine for this purpose.[3] It is active in doses of 2,000-4,000 mg, making it some 20 times more potent than regular ethanol.[4] 2-Methylbutan-2-ol is similar in structure to ethchlorvynol and methylpentynol. It is a byproduct of the fermentation of grain. [5]
References
- ↑ Index no. 603-007-00-2 of Annex VI, Part 3, to Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. OJEU L353, 31.12.2008, pp 1–1355 at p 477.
- ↑ Coblentz, Virgil The Newer Remedies: A reference manual for physicians, pharmacists, and students, 1899, <http://books.google.com/books?id=BRxKAAAAMAAJ&printsec=titlepage&source=gbs_summary_r&cad=0#PPA18,M1>.
- ↑ Lewis, Robert A. Lewis' Dictionary of Toxicology, 1998.
- ↑ Brandenberger, Hans; Maes, Robert A. A. Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists, 1997, <http://books.google.com/books?id=ZhYtynyC4kAC&printsec=frontcover&source=gbs_summary_r&cad=0#PPA401,M1>.
- ↑ Gould, George Milbry; Scott, R. J. E. The Practitioner's Medical Dictionary, 1910.
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This page was originally imported from Wikipedia, specifically this version of the article "2-Methyl-2-butanol". Please see the history page on Wikipedia for the original authors. This WikiChem article may have been modified since it was imported. It is licensed under the Creative Commons Attribution–Share Alike 3.0 Unported license. |
