Total synthesis of (-)-podophyllotoxin

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This page is for the project done by Eric Stefanowicz and Matt McCabe.

References

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2. “Podophyllotoxin”. Wikipedia, The Free Encyclopedia. 28 February 2010, 23:54. Wikimedia Foundation, Inc. Retrieved 30 March, 2010 from http://en.wikipedia.org/wiki/Podophyllotoxin

3. Moraes, R.M., H. Lata, E. Bedir, M. Maqbool, and K. Cushman. 2002. The American mayapple and its potential for podophyllotoxin production. p. 527–532. In: J. Janick and A. Whipkey (eds.), Trends in new crops and new uses. ASHS Press, Alexandria, VA. Retrieved 31 March, 2010 from http://www.hort.purdue.edu/newcrop/ncnu02/v5-527.html

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7. D. F. Taber. (6 September, 2004). Synthesis of (-)-Podophyllotoxin. Org. Chem. Highlights. Retrieved 24 March, 2010 from� http://www.organic-chemistry.org/Highlights/2004/06September.shtm

8. Reynolds, A.J. Scott, A.J. Turner, C.I. Sherburn, M.S. (2003). The Intramolecular Carboxyarylation Approach to Podophyllotoxin. JACS, 125, 12108-12109.

9. Gordaliza, M. (1 December, 2006). Podophyllotoxin: Sources, Extraction, and Preparation of Cytotoxic Analog Compounds. Retrieved 31 March, 2010 from http://old.iupac.org/publications/cd/medicinal_chemistry/Practica-VI-1.pdf

10. Li-She Gan, Zhen-Zhen Wang, and Chang-Xin Zhou. (2009). Solubility of Podophyllotoxin in Six Organic Solvents From (283.2 to 323.2). J. Chem. Eng. Data, 54, 160–161. Retrieved 31 March, 2010 from http://pubs.acs.org/doi/pdf/10.1021/je8007028

11. Wu, Y. Zhang, H. Zhao, Y. Zhao, J. Chen, J. Li, L. (2007). A New and Efficient Strategy for the Synthesis of Podophyllotoxin and Its Analogues. Organic Letters, 9, 1199-1202. Retrieved 31 March, 2010 from http://webproxy.potsdam.edu:2186/doi/pdf/10.1021/ol0630954

12. Wu, Y. Zhao, J. Chen, J. Pan, C. Li, L. Zhang, H. (2009). Enantioselective Sequential Conjugate Addition-Allylation Reactions: A Concise Total Synthesis of (+)-Podophyllotoxin. Organic Letters, 11, 597-600. Retrieved 31 March, 2010 from http://webproxy.potsdam.edu:2186/doi/pdf/10.1021/ol8026208

13. Ngan V. (2009). Podophyllotoxin. DermNet NZ. Retrieved 30 March, 2010 from http://www.dermnet.org.nz/treatments/podophyllotoxin.html

14. Canel, C. Moraes, R.M. Dayan, F.E. Ferreira, D. (2000). Podophyllotoxin. Phytochemistry, 54, 115-120.