Biochemistry and biophysics of proteins and membranes

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NERM
June 2 - 5, 2010
POTSDAM
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The design of synthetic nanomaterials with novel properties has often been inspired by the natural biology of living cells. Cells express an array of miniature protein machines supported by the molecular scaffolding of the cell membrane and its associated cytoskeleton. These biological nanodevices perform complex physiological functions such as movement, communication, transport, and sensory perception. This session features interesting talks in the broad area of biochemistry and biophysics delivered by basic scientists who investigate the structure and mechanism of cellular proteins and membranes using a variety of experimental techniques and approaches.

This session will be held on the afternoon of Friday, June 4th in Timerman 131.

Session organizer

Dr. Edward Moczydlowski

Prof. Edward Moczydlowski is Professor and Chair of the Department of Biology at Clarkson University. He has a BA in biological science from Cornell University and a PhD in biology from UC San Diego, with postdoctoral work at Harvard Medical School and Brandeis University. Prior to joining Clarkson in 2003, he was a Professor in the Departments of Pharmacology and Cellular and Molecular Physiology at Yale University School of Medicine from 1986-2003. He currently teaches courses in neurobiology and pharmacology at Clarkson and his various research contributions include publications in the area of ion channel mechanisms and molecular toxinology.

Confirmed speakers

  • Prof. Fred Sigworth, Professor of Cellular and Molecular Physiology, Yale University. Topic: "Cryo-electron microscopy of ion channel proteins."
  • Prof. Elizabeth Rhoades, Assistant Professor of Molecular Biophysics and Biochemistry, Yale University.
  • Prof. Gerald (Jerry) W. Feigenson, Professor, Dept. of Molecular Biology & Genetics, Cornell University. Topic: "Nano-scale phase separation involving lipid domains in biomembranes."
  • Prof. Susan P. Gilbert, Professor and Head, Department of Biology, Rensselaer Polytechnic Institute. Topic: "Mitotic Kinesin CENP-E Promotes Microtubule Plus-End Elongation."
Sigworth.jpg Rhoades.jpg Feigenson.jpg Gilbert.jpg
Dr. Sigworth Dr. Rhoades Dr. Feigenson Dr. Gilbert

Program content

Friday, June 4, 1:00 PM - 4:45 PM

Biochemistry and Biophysics of Proteins and Membranes
Timerman 131

Organizer/Presider: Edward Moczydlowski

1:00 310 3- and 4-Component Lipid Mixtures to Model Biomembranes: Macroscopic Phase Separation Occurs, as Well as Puzzling Nanometer-Scale Domains. Gerald W. Feigenson, Cornell University

1:40 311 α-Synuclein: Probing the Conformations of a Polymorphic Membrane-Binding Protein. Adam J. Trexler, Eva Sevcsik and Elizabeth Rhoades, Yale University

2:20 312 Coenzyme Q10 Production in the Filamentous Basidiomycete Sporidiobolus johnsonii. David D. Dixson1, Robert P. Doyle1 and Christopher N. Boddy2, (1)Syracuse University, (2)University of Ottawa

2:45 Intermission

3:00 313 Mitotic Kinesin CENP-E Promotes Microtubule Plus-End Elongation. Susan P. Gilbert and Harjinder S. Sardar, Rensselaer Polytechnic Institute

3:40 314 Tale of Two Quinones. Ruchira Chatterjee12, Nithya Srinivasan3, Sergey Milikisiyants1,2, Christopher S. Coates1,2, John H. Golbeck3 and K. V. Lakshmi1,2, (1)Rensselaer Polytechnic Institute, (2)Rensselaer Polytechnic Institute, (3)The Pennsylvania State University

4:05 Cryo-EM microscopy of membrane proteins. L. Wang, F.J. Sigworth, Yale University