New trends in chromatography

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June 2 - 5, 2010
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Chromatography has enjoyed over a century of development, culminating in Martin and Synge's award of the Nobel Prize in 1952. The fast development of liquid chromatographic techniques starting in the early 1970s has made HPLC the workhorse of analysis in various fields, such as biomedical, chemical, environmental and pharmaceutical research and development. Although a mature technology (mostly in theoretical aspects), unrelenting needs for ever more efficient and faster analysis have led to significant new developments in chromatography in recent years, notably ultra-high performance liquid chromatography (UPLC), monolithic columns and hydrophilic interaction chromatography (HILIC). UPLC has rapidly grown out of its infancy and moved into the analytical labs. The potential and application of UPLC for fast separation will be discussed in this session. Monolithic columns also hold great potential for very fast separations. The discussion will focus on the fabrication and application of newer monolithic columns. Finally, HILIC is being re-evaluated for its unique ability to retain polar compounds. The discussion on HILIC will focus on various HILIC phases and its application in biomedical and pharmaceutical fields.

This session will take place on the afternoon of Thursday, June 3rd in Kellas 102.

This session is sponsored by Thermo Fisher.

Session organizer

Dr. Yong Guo is currently Principal Scientist and team leader at Johnson & Johnson Pharmaceutical Research and Development based in Raritan, New Jersey. Dr. Guo received his Ph. D in analytical Chemistry from State University of New York at Buffalo, and completed his postdoctoral training at Institute of Biotechnology, National Research Council of Canada, Montreal. Dr. Guo is also an adjunct professor of Pharmaceutical Chemistry at Fairleigh Dickinson University, Madison NJ. His research interest is in peak capacity in gradient elution, UPLC and HILIC.

Dr. Guo will speak on "Polar Stationary Phases in Hydrophilic Interaction Chromatography: Retention and Selectivity".

Confirmed speakers

Prof. Colón
  • Prof. Luis A. Colón, Department of Chemistry, State University of New York at Buffalo: "New approaches to monolithic columns for HPLC".

Prof. Colon's research interests include: micro/nano-chemical analysis, capillary electrophoresis and electrochromatography, liquid chromatography, chromatographic stationary phases/materials, bioanalytical chemistry, drug analysis in biological fluids.

Prof. Oleschuk
* Richard Oleschuk, Queens University, Kingston, ON: "Monoliths and microstructured optical fibres as highly permeable supports for fluorous chromatography".

Program

Thursday, June 3, 1:30 PM - 5:35 PM

New Trends in Chromatography
Kellas 102

Organizer/Presider: Yong Guo

1:30 Introductory Remarks

1:35 232 HILIC-MS Sensitivity without Silica. Bob Myers1 and Luisa Pereira2, (1)Thermo Fisher Scientific, (2)Thermo Fisher Scientific

2:05 233 Polar Stationary Phases in Hydrophilic Interaction Chromatography: Retention and Selectivity. Yong Guo, Janssen Pharmaceutical Companies

2:35 234 New Approaches to Monolithic Columns for HPLC. Luis A. Colon, Wenjuan Guo, Stefan Vujcic and Ivonne M. Ferrer, University at Buffalo

3:15 Intermission

3:25 235 Monoliths and Microstructured Optical Fibres as Highly Permeable Supports for Fluorous Chromatography. Richard D. Oleschuk, Adam B. Daley and Zhenpo Xu, Queen’s University

4:05 236 New Column Technology That Closes the Performance Gap between HPLC and UHPLC Instrumentation. Jason A. Anspach, Carl Sanchez, Lawrence Loo, Gareth Friedlander, Jeff Layne and Tivadar Farkas, Phenomenex

4:35 237 New Pump Technology To Improve LC Performance under All Operating Conditions. Sergio Guazzotti1, Guenter Boehm2 and Thomas Preiswerk2, (1)Thermo Fisher Scientific, (2)Thermo Fisher Scientific

5:05 238 Pharmaceutical Process Testing Using Sub-2µm Liquid Chromatography Column Technology. Marie-Josée Rocheleau, Elaine Larouche and Cristina Salamu, Omega Laboratories Ltd